Biopsy

lBiopsy is the removal of tissue for the purpose of diagnostic examination (histopathological examination) .

Indications of Biopsy

lAny lesion that persists for more than 2 weeks with no apparent etiology

lAny inflammatory lesion that does not respond to local treatment after 10 to 14 days.

lPersistent hyperkeratotic changes in surface tissues.

lAny persistent tumescence, either visible or palpable beneath relatively normal tissue.

lInflammatory changes of unknown cause that persist for long periods

lLesion that interfere with local function

lBone lesions not specifically identified by clinical and radiographic findings

lAny lesion that has the characteristics of malignancy.

Types of Biopsy

lOral cytology

lAspiration biopsy

lIncisional biopsy

lExcisional biopsy

Cytology biopsy

l as a diagnostic screening procedure to monitor large tissue areas for dysplastic changes.
lfrequently used to screen for uterine cervix malignancy
lMay be helpful with monitoring postradiation changes, herpes, pemphigus.

Aspiration biopsy

lAspiration biopsy is the use of a needle and syringe to penetrate a lesion for aspiration if its contents.

lIndications:

–To determine the presents of fluid within a lesion

–To a certain the type of fluid within a lesion

–When exploration of an intraosseous lesion is indicated

incisional biopsy

lAn incisional biopsy is a biopsy that samples only a particular portion or representative part of a lesion.

lIf a lesion is large or has different characteristics in various locations more than one area (extensive lesions) may need to be sampled.

Indication:

–Size limitations

–Hazardous location of the lesion

–Great suspicion of malignancy

Excision biopsy

An excisional biposy implies the complete removal of the lesion.

lIndications:

–Should be employed with small lesions. ( Less than 1cm )

–The lesion on clinical exam appears benign.

–When complete excision with a margin of normal tissue is possible without mutilation.

Dangers of Biopsy:

الأربعاء، 30 مارس 2016